Methadone was developed in 1939 Germany by scientists working for I.G. Farbenkonzern at the Farbwerke Hoechst, (it is synthesised from 1,1-diphenylbutane-2-sulfonic acid and dimethylamino-2-chloropropane), who were looking for an synthetic opioid that could be created with readily available precursors to solve Germany’s opium shortage problem.
On September 11, 1941 Bockmühl and Ehrhart filed an application for [...]

Morphine is a pain killer used in medicine with real success, unfortunately many people misuse it. From morphine comes and the well known codeine, from the morphine comes and the “well known” heroin and a large number of opioids. And the easiness of passing from morphine to heroin is frightening. Morphine is just commonly treated [...]

Oxycodone can be administered orally, intranasally, via intravenous, intramuscular, subcutaneous injection or rectally. Some people are fast metabolizers resulting in reduced analgesic effect but increased adverse effects, while others are slow metabolisers resulting in increased toxicity without improved analgesia. The dose of OxyContin must be reduced in patients with reduced hepatic function.
Oxycodone is approximately 1.5–2 [...]

One of the most prescribed narcotic analgesics for pain relief is OxyContin. It is true that it works as painkiller for severe injuries like dislocations, fractures, arthritis, lower back pain, but it is also used illicitly as drug on the street due to it’s main component, oxycodone.
Oxycodone can be found in many narcotic analgesics like [...]

Morphine is considered as one of the most important ingredients of opium and a prototypical Opioid. It acts directly on the principal nerve system that relieves the pain. It is a very powerful drug and effective one that works as an efficient painkiller. However, people often use it the way it should not be; they [...]