Methadone is a synthetic opioid, developed first time in Germany in 1937, used medically as an analgesic, antitussive and a maintenance anti-addictive for use in patients on opioids. Although chemically unlike morphine or heroin, methadone also acts on the opioid receptors and thus produces many of the same effects. Methadone is also used in managing [...]

 
Even if it is used only for medical purposes, morphine has and some critical side effects over the human body, others than the ones expected from it as medicinal drug, and, of course, we must count the ones it has as recreational drug. Here you have some of them.
Like loperamide and other opioids, morphine acts [...]

Mundipharma, a pharmaceutical company that distribute oxycodone and oxycontine in Australia, China and Europe, has published in 2008 review over prolonged-release oxycodone (i.e., OxyContin), where they claimed that oxycodone is superior to placebo in randomized controlled trials concerning several diseas. I can not pronounce over the credibility of this review since it was written by [...]

The human body and the brain contain opioid receptors called endorphins, our own natural pain-killing substances produced whenever our body pass through emergency moments of shock or injury. Heroin binds rapidly with endorphin receptors, extending and magnifying their natural painkilling effect.
The result is a sensation of pleasurable, known as “high” “rush.” The user experiences a [...]