Nicotine has very powerful effects on arteries throughout the body. Nicotine is a stimulant, it raises blood pressure, and is a vasoconstrictor, making it harder for the heart to pump through the constricted arteries. It causes the body to release its stores of fat and cholesterol into the blood. It has been speculated that nicotine [...]

 
Technically, nicotine is not significantly addictive, as nicotine administered alone does not produce significant reinforcing properties. However, only after coadministration with an MAOI, such as those found in tobacco, nicotine produces significant behavioral sensitization, a measure of addiction potential. This is similar in effect to amphetamine.
Modern research shows that nicotine acts on the brain to [...]

 
Cotinine is a byproduct of the metabolism of nicotine which remains in the blood for up to 48 hours. It can therefore be used as an indicator of a person’s exposure to nicotine. Nicotine’s mood-altering effects are different by report: in particular it is both a stimulant and a relaxant. First causing a release of [...]

 
As with any other drugs, the body builds up a tolerance for heroin. The addict will have to use larger amounts in order to achieve the high. In time, the addict will have to take heroin several times per day trying to avoid the withdrawal symptoms. The repeated use leads to addiction, whether you are [...]