Nicotine improves ADHD symptoms and appears to have effects in the brain that are similar to those of stimulants. Although such findings should certainly not encourage anyone to smoke, some studies are focusing on benefits of nicotine therapy in adults with ADHD.
However, when the metabolites of nicotine were isolated and their effect on first the [...]

 
The curious thing about nicotine is that, in certain situations, smoking has been observed to apparently be of therapeutic value to patients. And we are not reffering at the fact that it is used in medical field, as the morfine and other prescription drugs. These cases are often referred to as “Smoker’s Paradoxes”.
Although in most [...]

 
Nicotine has very powerful effects on arteries throughout the body. Nicotine is a stimulant, it raises blood pressure, and is a vasoconstrictor, making it harder for the heart to pump through the constricted arteries. It causes the body to release its stores of fat and cholesterol into the blood. It has been speculated that nicotine [...]

 
A lethal dose of nicotine for rats is 50 mg/kg and for mice 3 mg/kg. Comparing with that, for adult humans 40–60 mg (0.5-1.0 mg/kg) can be a lethal dose. Nicotine therefore has a high toxicity in comparison to many other alkaloids such as cocaine, which has an LD50 of 95.1 mg/kg when administered to [...]

 
Technically, nicotine is not significantly addictive, as nicotine administered alone does not produce significant reinforcing properties. However, only after coadministration with an MAOI, such as those found in tobacco, nicotine produces significant behavioral sensitization, a measure of addiction potential. This is similar in effect to amphetamine.
Modern research shows that nicotine acts on the brain to [...]